Arrhythmias & electrophysiology

Combination of slow pathway late activation maps and voltage gradient maps in guidance of atrioventricular nodal reentrant tachycardia cryoablation

Heart RhythmPublished Cohort study with historical controls

Authors' conclusion

For AVNRT cryoablation, SPLAM could effectively guide the localization of slow pathway ablation sites and was particularly beneficial in patients with multiple slow pathways.

Study context

Population
Consecutive patients with atrioventricular nodal reentry tachycardia (AVNRT) undergoing cryoablation (age 16.5 ± 8.2 and 15.5 ± 7.3 years)
Participants
36 vs 37
Exposure
Study vs Control
  • Studyn = 36
  • Controln = 37reference
Outcome
Procedural effectiveness
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

GroupValueCryomapping attempts (median)Cryoablation applications (median)
Study100%31
Control100%52

Value

Study100%
Control100%

Cryomapping attempts (median)

Study3
Control5

Cryoablation applications (median)

Study1
Control2
  • Study vs Control: P = 0.012 — cryomapping attempts
  • Study vs Control: P < 0.001 — cryoablation applications

Observational data: associations, not effects.

Further findings

Recurrence · median follow-up 14.6 (study) and 18.3 (control) months

P = 0.402

Total procedural time and acute success

Total procedural times comparable

Koch triangle mapping (study procedure)

Mapping time (minutes)
11.8 ± 3.6
Points collected
1562 ± 581

Agreement of mapping targets with final successful lesion site

Low-voltage bridge (LVB) could not be defined
6 patients (16.7%)
LVB not compatible with final successful lesion
6 (16.7%)
Slow pathway late activation mapping (SPLAM) wave collision point defined and compatible with final successful lesion site in all patients, incl. multiple slow pathways

Original publication

Combination of slow pathway late activation maps and voltage gradient maps in guidance of atrioventricular nodal reentrant tachycardia cryoablation. Heart Rhythm. Published 17 April 2023. doi:10.1016/j.hrthm.2023.04.006

Summarised from the published abstract; every number is checked against it

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