Aortic & peripheral vascular diseaseCross-sectional study
Community-based recruitment with ankle brachial index testing to identify peripheral artery disease participants for randomized clinical trials
- retrospective, cross-sectional study
Authors' conclusion
Approximately 23% of people living in the community who underwent ABI testing as part of a clinical trial recruitment method had PAD. Compared to PAD participants from the medical center, those identified from the community included more people traditionally underrepresented in clinical trials and had greater walking impairment TRIAL REGISTRATION: ClinicalTrials.gov identifier: (NCT03743636, NCT04794530, NCT05624125, NCT02593110, NCT03054519, NCT06032065, NCT06165016, NCT03363165, NCT03871075, NCT06399900, NCT02538900, NCT01408901, NCT04228978, NCT06657976).
Study context
- Population
- People with peripheral artery disease (PAD) recruited for clinical trials of interventions to improve walking performance, Chicago or New Orleanspeople who responded to a postcard and underwent ankle brachial index (ABI) testing, 669 (23.4%) had ABI < 0.90
- Participants
- 2,856 people
- Exposure
- PAD participants identified with community-based recruitment vs PAD participants recruited from the medical center
- PAD participants from the communityn = 669
- PAD patients from a medical centern = 275
Main finding
As reported in the abstract
Had ABI < 0.90 (of 2,856 tested)
669 (23.4%)
Observational data: associations, not effects.
Further findings
Black race
Household income < $50,000
Without a college degree
6-minute walk distance
- Black race: P < .001
- Household income < $50,000: P = .015
- Without a college degree: P = .016
- 6-minute walk distance: P = .002
Original publication
Summarised from the published abstract; every number is checked against it