Coronary disease & ACS

Comparing the Classification of Percutaneous Coronary Interventions Using the 2012 and 2017 Appropriate Use Criteria: Insights From 245,196 Patients in the NCDR CathPCI Registry

Am Heart JPublished Retrospective registry study

Authors' conclusion

In this contemporary analysis of patients undergoing PCI in the United States, only fair agreement between the 2012 and updated 2017 AUC was observed.

Study context

Population
Elective percutaneous coronary intervention (PCI) cases in the NCDR CathPCI registry, March 1, 2018 to June 30, 2021
Participants
245,196 cases1,669 centres
Exposure
2017 AUC vs 2012 AUC classification of PCI appropriateness
Outcome
Concordance of PCI appropriateness classification (Cohen's Kappa)
Methodological detailsmulticentre, 1669 centres
  • Multicentre
  • 1669 centres

Main finding

As reported in the abstract

Overall fair agreement, Cohen's kappa
0.40 (95% CI 0.396-0.403)
2012 AUC: appropriate
44%
2012 AUC: uncertain
28%
2012 AUC: inappropriate
16%
2017 AUC: appropriate
34%
2017 AUC: may be appropriate
56%
2017 AUC: rarely appropriate
4%

Observational data: associations, not effects.

Further findings

Not mappable PCI

Characteristics of reclassified PCI

Became non-appropriate vs remained appropriate: more likely asymptomatic, less likely on anti-anginals, less likely complex lesions
Became appropriate vs became non-appropriate: more atypical and non-anginal symptoms, less likely positive functional tests

Safety

Procedural related outcomes

Similar across all groups

Original publication

Comparing the Classification of Percutaneous Coronary Interventions Using the 2012 and 2017 Appropriate Use Criteria: Insights From 245,196 Patients in the NCDR CathPCI Registry. Am Heart J. Published 9 October 2022. doi:10.1016/j.ahj.2022.10.002

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