Heart failure & cardiomyopathies
Comparing Life’s Simple 7 and Life’s Essential 8 With Risk of Heart Failure
Corrected 23 Oct 2026: The values shown beside the hazard ratio were the share of participants with low and high cardiovascular health, not the heart-failure rate; removed.
Main finding · HFResult — go to the resultHazard ratio 0.18 95% CI 0.12–0.26Authors' conclusion
LS7 and LE8 differ in scoring and CVH classification. While a strong inverse association exists between LE8 score classification and HF risk, the association is graded over the whole LE8 range, suggesting that nuances may be overlooked when using the proposed CVH classification for exploring HF risk.
Study context
- Population
- Participants of the EPIC-NL cohort, predominantly female (74%), median age 52 yearsEPIC-NL cohort
- Participants
- 37,803 participants
- Exposure
- High vs low cardiovascular health (CVH) by LE8; LE8 vs LS7 classification
- Outcome
- Risk of HF by LE8 score
Main finding
HF
Hazard ratio
0.18
95% CI 0.12–0.26
As reported in the abstract
Observational data: associations, not effects.
Further findings
Moderate CVH classification, LE8 vs LS7
- Moderate CVH by LE8
- 75%
- Moderate CVH by LS7
- 36%
- Upward shift from LS7 low CVH to LE8 moderate CVH
- 90%
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →