Comparison of Care and Outcomes for Myocardial Infarction by Heart Failure Status Between United Kingdom and Japan
Authors' conclusion
Important differences in the care and outcomes for STEMI with heart failure exist between the United Kingdom and Japan. Specifically, in the United Kingdom, there was a lower rate of pPCI, and in Japan, fewer patients were prescribed beta blockers and hospital length of stay was longer.
Study context
- Population
- Patients admitted with ST elevation myocardial infarction (STEMI), UK and Japan, 2012–2017, stratified by Killip class (1: no congestive HF; 2–3: congestive HF; 4: cardiogenic shock)
- Exposure
- UK vs Japan, by HF status
- Outcome
- Use of treatments and in-hospital death
- Follow-up
- In-hospital
Methodological detailstwo nationwide databases, case mix standardized
- Two nationwide databases
- Case mix standardized
Main finding
As reported in the abstract
In-hospital mortality
CSRR
1.80
95% CI 1.73–1.87; P < 0.001
Killip 2-3: 15.8% vs 6.4%
CSRR
1.11
95% CI 1.08–1.13; P < 0.001
Killip 4: 36.9% vs 36.3%
Observational data: associations, not effects.
Further findings
Primary PCI use, by Killip class
Killip 1
Killip 2-3
Killip 4
Beta-blocker use · consistently lower in Japan across Killip classes
Length of hospital stay
Age
Original publication
Comparison of Care and Outcomes for Myocardial Infarction by Heart Failure Status Between United Kingdom and Japan. ESC Heart Fail. Published 3 February 2023. doi:10. 1002/ ehf2. 14290
Summarised from the published abstract; every number is checked against it