Coronary disease & ACS

Comparison of Outcomes Between 1- and 2-Stent Techniques for Medina Classification 0.0.1 Coronary Bifurcation Lesions

JACC Cardiovasc IntervPublished Registry-based cohort study

Main findingResult — go to the resultHazard ratio 1.034 95% CI 0.541–1.977

Study context

Participants
345 participants
Exposure
1-stent vs 2-stent strategy
  • 1 stentn = 209
  • 2 stentn = 136reference
Outcome
MACE:
  • All-cause death
  • MI
  • Target vessel revascularization
  • Stent thrombosis
Follow-up
800 days
Methodological detailspooled patient-level analysis of COBIS II, COBIS III and RAIN registries, patient-level merged registries, multicentre
  • Pooled patient-level analysis of COBIS II, COBIS III and RAIN registries
  • Patient-level merged registries
  • Multicentre

Main finding

As reported in the abstract

Hazard ratio

1.034

95% CI 0.541–1.977

P = 0.92

By group

1 stentvs 2 stent
HR 1.034 (95% CI 0.541–1.977); P = 0.92

Observational data: associations, not effects.

Further findings

Use of 1-stent strategy over time

2003-2009
36.0%
2010-2014
47.4%
2015-2017
90.4%
Trend
P for trend < 0.001

Major adverse cardiac event (MACE), stratified into 3 groups (1-stent crossover only, 1-stent with strut opening, 2-stent)

Risk of MACE not significantly different across the 3 groups

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Comparison of Outcomes Between 1- and 2-Stent Techniques for Medina Classification 0.0.1 Coronary Bifurcation Lesions. JACC Cardiovasc Interv. Published 9 August 2023. doi:10.1016/j.jcin.2023.06.013

Composed by AI from the published abstract and checked against it. How Briefs are made →

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