Heart failure & cardiomyopathiesDiagnostic or prognostic study
Comparison of the 2016 American Society of Echocardiography (ASE)/EACVI and 2025 ASE guidelines for assessing left atrial pressure in patients with normal left ventricular ejection fraction
- prospective diagnostic comparison of guidelines
Authors' conclusion
The 2025 guidelines significantly improved the feasibility of assessing LAP and enhanced ELAP detection rates and applicability while maintaining comparable accuracy.
Study context
- Population
- Patients with normal left ventricular ejection fraction with echocardiographic data and left atrial pressure (LAP) measurementspatients with echocardiographic data and LAP measurements
- Participants
- 119 patients
- Comparison
- 2025 ASE guidelines vs 2016 ASE/EACVI guidelines
Performance
As reported in the abstract
Diagnostic performance for ELAP
| Test or model | Sensitivity | Feasibility | Specificity | Positive predictive value | Negative predictive value | Overall accuracy |
|---|---|---|---|---|---|---|
| 2025 ASE guidelines | 86.4% [75.7-93.6] | 100% [98.0-100] | 81.8% [73.8-88.2] | 72.2% [63.7-79.3] | 91.7% [85.6-95.3] | 83.4% [77.3-88.5] |
| 2016 ASE/EACVI guidelines | 54.0% [39.3-68.2] | 78.1% [72.2-84.0] | 94.8% [88.3-98.3] | 84.4% [68.9-92.9] | 79.8% [74.5-84.3] | 80.8% [73.5-86.9] |
Original publication
Comparison of the 2016 ASE/EACVI and 2025 ASE guidelines for assessing left atrial pressure in patients with normal left ventricular ejection fraction. Eur Heart J Cardiovasc Imaging. Published 2 June 2026. doi:10.1093/ehjci/jeag134
Summarised from the published abstract; every number is checked against it