Complete revascularization in patients with acute myocardial infarction and multivessel disease: Pooled analysis of Kaplan-Meier-derived individual-patient-data
Pooled result · MACEResult — go to the resultHazard ratio 0.59 95% CI 0.54–0.66Authors' conclusion
Complete revascularization results in lower risks of all-cause and cardiovascular mortality, MI, unplanned repeat revascularizations and MACE in patients with acute MI and multivessel disease.
Study context
- Population
- Patients with acute MI and multivessel disease without cardiogenic shock
- Participants
- 9,658 patients9 RCTs
- Comparison
- Complete vs incomplete revascularization
- Complete revascularizationn = 4,671
- Outcome
- Major adverse cardiac events (MACE)
- Follow-up
- 5 years
Methodological detailsreconstructed individual-patient-data from published Kaplan-Meier curves
- Reconstructed individual-patient-data from published Kaplan-Meier curves
Pooled result
As reported in the abstract
Hazard ratio
0.59
95% CI 0.54–0.66
P < 0.001
Complete revascularizationvs Incomplete revascularization
HR 0.59 (95% CI 0.54–0.66); P < 0.001
Further pooled results
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| All-cause mortality · 5 years | 0.64 (0.56–0.72) | P < 0.001 | |
| CV mortality · 5 years | 0.82 (0.71–0.95) | P = 0.008 | |
| MI · 5 years | 0.69 (0.55–0.87) | P < 0.001 | |
| Unplanned repeat revascularizations · 5 years | 0.62 (0.54–0.71) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
Original publication
Complete revascularization in patients with acute myocardial infarction and multivessel disease: Pooled analysis of Kaplan-Meier-derived individual-patient-data. Am Heart J. Published 2 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →