Arrhythmias & electrophysiology

Components of the Atrial fibrillation Better Care pathway for holistic care of patients with atrial fibrillation: a win ratio analysis from the COOL-AF registry

EuropacePublished Registry cohort study

Authors' conclusion

Management of AF patients according to each component of the ABC pathway is associated with better clinical outcomes compared to those non-compliant to ABC pathway.

Study context

Population
AF patients in the COOL-AF registry, followed every 6 months until 3 years
Participants
3,405 patients
Exposure
ABC-compliant vs ABC-not-compliant
Outcome
Clinical outcomes by compliance with each ABC pathway component, hierarchical win ratio
Follow-up
Until 3 years
Methodological detailswin ratio analysis of the COOL-AF registry, hierarchical win ratio analysis
  • Win ratio analysis of the COOL-AF registry
  • Hierarchical win ratio analysis

Main finding

As reported in the abstract

Hierarchical composite (win ratio)
Each group vs ABC-not-compliantWin ratio (CI)P value
ABC-compliant
1.57(1.35–1.83)
P < 0.001
ABC-compliantadding TTR data to compliant criteria for those on warfarin
2.28(1.89–2.75)
P < 0.001
A-compliantplus TTR data; vs not compliant
1.81(1.51–2.12)
P < 0.001
B-compliantvs not compliant
1.82(1.53–2.16)
P < 0.001
C-compliantvs not compliant
1.39(1.18–1.62)
P < 0.001

Observational data: associations, not effects.

Original publication

Components of the Atrial fibrillation Better Care pathway for holistic care of patients with atrial fibrillation: a win ratio analysis from the COOL-AF registry. Europace. Published 16 September 2024. doi:10.1093/europace/euae237

Summarised from the published abstract; every number is checked against it

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