Heart failure & cardiomyopathiesCohort study
Comprehensive multiple risk factor control in cancer survivors to mitigate heart failure risk: insights from a prospective cohort study
- Prospective cohort study
- matched controls
Authors' conclusion
Among cancer survivors, we observed a graded inverse association between the level of joint risk factor control and the risk of HF.
Study context
- Population
- Cancer survivors, UK Biobank, with matched controls without cancercancer survivors + matched controls
- Exposure
- Degree of joint risk factor control among cancer survivors
- Matched controlsn = 57,864
- Outcome
- Incident HF
- Follow-up
- Median 12.54 years
Main finding
As reported in the abstract
Hazard ratio (95% CI)
Each additional controlled risk factor12% reduction per factor; adjusted
0.88(0.81–0.96)
≥5 risk factors controlled vs Lowest risk factor control24% lower HF risk
0.76(0.61–0.95)
- Heart failure (HF) events: cancer survivors
- 572
- HF events: matched controls
- 1851
Observational data: associations, not effects.
Original publication
Comprehensive multiple risk factor control in cancer survivors to mitigate heart failure risk: insights from a prospective cohort study. Eur J Prev Cardiol. Published 13 November 2025. doi:10.1093/eurjpc/zwaf711
Summarised from the published abstract; every number is checked against it