Acute cardiac care & resuscitation

Comprehensive non-invasive haemodynamic assessment in acute decompensated heart failure-related cardiogenic shock: a step towards echodynamics

Eur Heart J Acute Cardiovasc CarePublished Prospective diagnostic accuracy study

Authors' conclusion

Echocardiographic estimation of haemodynamics and subsequent phenotypization of CS is feasible with good agreement with invasive evaluation.

Study context

Population
ADHF-related cardiogenic shock (SCAI shock stage ≥B) undergoing right heart catheterization (RHC), 2020–2022
Participants
101 participants
Comparison
Echocardiographic vs invasive haemodynamic assessment
Outcome
Correlation between echocardiographic and invasive assessment of haemodynamics (CI, WP, PAP, CPO, PAPi)
Methodological detailsconsecutive patients
  • Consecutive patients

Performance

As reported in the abstract

Correlation of echocardiographic with invasive haemodynamics

CI, systolic pulmonary artery pressures (PAP), RAP and cardiac power output (CPO): good correlation (Pearson r)

r > 0.8

ePAPi: moderate correlation

r = 0.67

PVR: moderate correlation

r = 0.51

Further findings

Diagnostic accuracy of echocardiographic estimates vs invasive thresholds

eCI for low output state (CI ≤2.2 L/min/m²): sensitivity / specificity
0.97 / 0.73
eWP for elevated filling pressures (wedge pressure (WP) >15 mmHg): sensitivity / specificity
0.84 / 0.55
ePAPs for PAPs ≥35 mmHg: sensitivity / specificity
0.87 / 0.63
eCPO for CPO <0.6 W: sensitivity / specificity
0.76 / 0.85
ePAPi for pulmonary artery pulsatility index (PAPi) <1.85: sensitivity / specificity
0.89 / 0.92

Agreement of echocardiographic cardiogenic shock (CS) phenotyping with invasive classification

Good agreement, K value
0.457
P value
P < 0.001

Original publication

Comprehensive non-invasive haemodynamic assessment in acute decompensated heart failure-related cardiogenic shock: a step towards echodynamics. Eur Heart J Acute Cardiovasc Care. Published 16 July 2024. doi:10.1093/ehjacc/zuae087

Summarised from the published abstract; every number is checked against it

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