Arrhythmias & electrophysiologyResearch article
Computer-aided characterization of the arrhythmogenic substrate after myocardial infarction
- Narrative review
Study context
- Population
- Post-MI ventricular tachycardia (VT)
Main finding
As reported in the abstract
Computer-aided characterisation of the post-MI arrhythmogenic substrate (imaging, invasive and non-invasive mapping, computational simulation, AI)
- High-resolution cardiac imaging enables detailed visualisation of structural abnormalities, including heterogeneous scar architecture and fatty infiltration
- Invasive mapping gives insight into local electrophysiological properties; non-invasive mapping offers complementary views of global electrical patterns
- Computational simulations integrating these modalities give mechanistic insights into arrhythmia initiation and maintenance, particularly in post-MI VT
- AI applications enhance substrate analysis through automated feature extraction and pattern recognition, enabling more sophisticated risk stratification
- Early evidence suggests improved ablation outcomes and better risk prediction; significant challenges remain in validation, standardisation and clinical implementation
- narrative review
Original publication
Computer-aided characterization of the arrhythmogenic substrate after myocardial infarction. Europace. Published 9 January 2026. doi:10.1093/europace/euag003
Summarised from the published abstract; every number is checked against it