Valvular & structural heart diseaseCohort study

Congestion Patterns in Severe Tricuspid Regurgitation and Transcatheter Treatment: Insights from a Multicentre Registry

Eur J Heart FailPublished

  • Registry-based cohort study
  • multicentre
  • international

Authors' conclusion

In this large cohort of invasively characterized patients undergoing TTVI, congestion patterns involving right-sided congestion were associated with low procedural success and higher mortality rates after TTVI.

Study context

Population
Patients with severe tricuspid regurgitation (TR) undergoing right heart catheterization before transcatheter tricuspid valve intervention (TTVI)
Participants
813 patients
Exposure
Congestion patterns by invasive right atrial pressure (RAP) and pulmonary capillary wedge pressure (PCWP) before TTVI
Outcome
Mortality
Follow-up
2 years

Main finding

As reported in the abstract

2-year mortality
Mean RAP and PCWP associated with 2-year mortality (Youden cut-offs 17 mmHg and 19 mmHg)
P < 0.01 for all

Observational data: associations, not effects.

Original publication

Congestion Patterns in Severe Tricuspid Regurgitation and Transcatheter Treatment: Insights from a Multicentre Registry. Eur J Heart Fail. Published 4 April 2024. doi:10.1002/ejhf.3235

Summarised from the published abstract; every number is checked against it