Valvular & structural heart diseaseCohort study

Contemporary 1-Year Outcomes of Mitral Valve-in-Ring With Balloon-Expandable Aortic Transcatheter Valves in the U.S.

JACC Cardiovasc IntervPublished

  • Registry study
  • multicentre

Authors' conclusion

MViR with third-generation balloon-expandable aortic transcatheter heart valves is associated with a significant reduction in mitral regurgitation and improvement in symptoms at 1 year, but with elevated valvular gradients and a high reintervention rate.

Study context

Population
Patients undergoing mitral valve-in-ring (MViR) after surgical mitral valve repair with an annuloplasty ring, STS/ACC TVT Registry, August 2015–December 2022
Participants
820 patients · 236 sites

Main finding

As reported in the abstract

Outcomes at 1 year after MViR · 1 year
All-cause mortality at 1 year
22.4%
Reintervention rate
9.1%
NYHA class I to II
75.6%
KCCQ score increase (points)
25.9 ± 29.1
Mean mitral valve gradient (mm Hg)
8.4 ± 3.4
≤ mild mitral regurgitation
91.7%

Observational data: associations, not effects.

Further findings

Procedural and 30-day outcomes

Transseptal access
93.9%
Technical success
88%
All-cause mortality at 30 days
8.3%

Original publication

Contemporary 1-Year Outcomes of Mitral Valve-in-Ring With Balloon-Expandable Aortic Transcatheter Valves in the U.S. JACC Cardiovasc Interv. Published 8 April 2024. doi:10.1016/j.jcin.2024.02.012

Summarised from the published abstract; every number is checked against it