Valvular & structural heart disease
Contemporary guideline-directed management of patients with severe aortic valve stenosis
Authors' conclusion
TAVI was routinely performed in low surgical risk patients in 2021 with two-thirds of all severe AS patients undergoing TAVI, thereby applying the latest European guidelines.
Study context
- Population
- Consecutive patients with severe aortic stenosis (AS) referred for intervention in East Denmark in 2021, all with cardiac computed tomography (CT) before Heart Team meeting
- Participants
- 672 patients
- Exposure
- Transcatheter aortic valve implantation (TAVI) vs surgical aortic valve replacement (SAVR)
- TAVIn = 439
- SAVRn = 189reference
- Outcome
- Heart Team decision and treatment received
Methodological detailsconsecutive patients, multidisciplinary Heart Team evaluation, All patients had cardiac CT before the Heart Team meeting; outcomes prospectively recorded
- Consecutive patients
- Multidisciplinary Heart Team evaluation
- All patients had cardiac CT before the Heart Team meeting; outcomes prospectively recorded
Main finding
As reported in the abstract
Referred for TAVI after Heart Team discussion
N=456, 68%
Received Heart Team-recommended treatment
94%
N=632
Observational data: associations, not effects.
Further findings
Age · TAVI older and more comorbid
P < 0.001
Index hospitalisation length
30-day mortality (overall)
- Overall 30-day mortality
- 1.1%
- 30-day clinical outcomes satisfactory for both treatment groups
Original publication
Contemporary guideline-directed management of patients with severe aortic valve stenosis. EuroIntervention. Published 15 January 2024. doi:10.
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