Valvular & structural heart diseaseCohort study
Contemporary Outcomes of the Ross Procedure in Adults
- Prospective cohort study
- single-centre
- consecutive patients
Authors' conclusion
In a large contemporary adult cohort with comprehensive follow-up, the Ross procedure was associated with excellent long-term survival, durable valve performance, and low reintervention rates, including in patients with preoperative aortic regurgitation and those >50 years of age.
Study context
- Population
- Adults undergoing the Ross procedure at a high-volume tertiary centre, 2011–2019 (mean age 47 ± 12 years; 73% male)98% follow-up completeness
- Participants
- 455 adults
- Outcome
- Operative safety, long-term survival, reinterventions, valve hemodynamics and autograft root dimensions
Main finding
As reported in the abstract
- Operative mortality
- 0.4% (n = 2)
- Cumulative incidence of autograft reintervention at 12 years
- 1.1% ± 0.5%
- Cumulative incidence of pulmonary homograft reintervention at 12 years
- 1.9% ± 0.9%
- Any cardiac reintervention at 12 years
- 3.5% ± 1.0%
- Mean aortic valve gradient at 12 years
- 4.0 ± 0.2 mm Hg
Observational data: associations, not effects.
Further findings
| Outcome | Aortic regurgitation | Aortic stenosis | P value |
|---|---|---|---|
| Autograft reintervention at 12 years, by preoperative aortic regurgitation vs aortic stenosis (subgroup) · no difference | 1.2% ± 1.2% | 1.1% ± 0.6% | P = 0.39 |
Safety
Patient-prosthesis mismatch and permanent pacemaker implantation
- Permanent pacemaker implantation
- 0.8% (n = 3)
- No patient-prosthesis mismatch
Original publication
Contemporary Outcomes of the Ross Procedure in Adults. J Am Coll Cardiol. Published 23 June 2026. doi:10.1016/j.jacc.2026.03.173
Summarised from the published abstract; every number is checked against it