Aortic & peripheral vascular diseaseCohort study
Contemporary Practice Patterns and Outcomes of Endovascular Revascularization of Acute Limb Ischemia
- Retrospective registry study
- nationwide
- multicenter
Authors' conclusion
Patients with pre-existing medical comorbidities and those with diminished limb viability were more likely to suffer adverse outcomes. Adverse event rates remain high for patients affected by acute limb ischemia despite its declining incidence.
Study context
- Population
- Patients undergoing peripheral vascular intervention for acute limb ischemia, NCDR PVI Registry, 2014–2020
- Participants
- 3,541 endovascular procedures
- Outcome
- Composite of:
- All-cause mortality
- Major amputation
- Follow-up
- During index hospitalization
Main finding
As reported in the abstract
Death and amputation during hospitalization · index hospitalization
Death
132 (3.7%)
Amputation
77 (2.2%)
Observational data: associations, not effects.
Further findings
Independent predictors of death or amputation (multivariable logistic regression)
| Comparison | OR (95% CI) | |
|---|---|---|
| Severe lung disease | 1.72 (1.17–2.52) | |
| Rutherford Class IIb | 2.44 (1.62–3.65) | |
| Preprocedure hemoglobin | 0.78 (0.73–0.85) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | OR (95% CI) |
|---|---|
| Independent predictors of death or amputation (multivariable logistic regression) — End-stage renal disease · CI as printed | 3.94 (0.73–0.85) |
Device use
- Thrombolysis catheters
- 27.7% (n = 981)
- Thrombectomy catheters
- 3.9% (n = 138)
Safety
Complications
- Bleeding within 72 hours of intervention
- 6.7%
- Thrombosis
- 2.8%
Original publication
Contemporary Practice Patterns and Outcomes of Endovascular Revascularization of Acute Limb Ischemia. JACC Cardiovasc Interv. Published 28 October 2024. doi:10.1016/j.jcin.2024.09.010
Summarised from the published abstract; every number is checked against it