Coronary disease & ACSCohort study
Contemporary Trends, Characteristics, and Outcomes of Patients Undergoing Percutaneous Coronary Intervention for Stent Thrombosis
- Retrospective cohort study
- registry-based
- nationwide
Authors' conclusion
In this contemporary, nationwide, real-world analysis, there was no temporal change in the frequency of PCI for ST. Most STs were early or very late. PCI for ST was associated with a higher rate of in-hospital adverse outcomes.
Study context
- Population
- Patients undergoing percutaneous coronary intervention (PCI) for acute MI, NCDR CathPCI registry, US, April 2018–June 2023
- Participants
- 2,023,032 patients
- Exposure
- PCI for stent thrombosis (ST) vs PCI for no ST
- STn = 57,268
Main finding
As reported in the abstract
In-hospital outcomes, PCI for ST vs non-ST · in-hospital
ST vs No STAdjusted odds ratio (95% CI)
MACE
1.24(1.19–1.29)
all-cause mortality
1.17(1.12–1.22)
recurrent MI
1.80(1.63–1.98)
Observational data: associations, not effects.
Further findings
- Frequency of PCI for ST
- 2.8% · 57,268 of 57,268
Frequency of PCI for ST
- No temporal change in the frequency of PCI for ST during the study period
Timing of ST
- Early
- 18,189 of 55,351 [31.8%]
- Late
- 8,825 of 55,351 [15.4%]
- Very late
- 28,337 of 55,351 [49.5%]
- Unknown
- 1,917 of 55,351 [3.4%]
Safety
| Outcome | aOR (95% CI) | |
|---|---|---|
| Major bleeding · in-hospital | 1.18 (1.15–1.22) | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Contemporary Trends, Characteristics, and Outcomes of Patients Undergoing Percutaneous Coronary Intervention for Stent Thrombosis. JACC Cardiovasc Interv. Published 9 March 2026. doi:10.1016/j.jcin.2025.11.045
Summarised from the published abstract; every number is checked against it