Arrhythmias & electrophysiologyCohort study
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome
- Multicentre cohort study
- 12 international centres
Authors' conclusion
Continuous rhythm monitoring with ILRs in young patients with BrS detects a broad range of arrhythmias. Ventricular arrhythmias occur predominantly in patients with spontaneous type 1 electrocardiograms and during fever. Despite the young age, bradyarrhythmias and atrial arrhythmias are frequent and represent the cause of arrhythmic syncope in 60% of patients.
Study context
- Population
- Children and adolescents (<18 years) with Brugada syndrome with an implantable loop recorder
- Participants
- 147 children
- Exposure
- Pediatric vs Adolescents
- Pediatricn = 77
- Adolescentsn = 70
- Outcome
- Arrhythmia prevalence during continuous implantable loop recorder (ILR) monitoring
- Follow-up
- Median 3.6 years (Q1-Q3: 1.6-4.8 years)
Main finding
As reported in the abstract
Any arrhythmic event
33 (22.4%)
Atrial events
15 (10.2%)
Bradyarrhythmic events
16 (10.9%)
Ventricular arrhythmias (all with spontaneous Brugada syndrome (BrS); fever-related in one-half)
4
Observational data: associations, not effects.
Further findings
Cause of recurrent syncope during follow-up
- True arrhythmic syncope documented
- 5 (17.8%)
- Due to bradyarrhythmias or atrial arrhythmias
- 3 cases (60%)
Original publication
Summarised from the published abstract; every number is checked against it