Conventional Versus Compression-Only Versus No-Bystander Cardiopulmonary Resuscitation for Pediatric Out-of-Hospital Cardiac Arrest
Authors' conclusion
In this population-based study of pediatric OHCA in Japan, both conventional and compression-only CPR were associated with superior outcomes compared with no-bystander CPR. Unadjusted outcomes with conventional CPR were superior to compression-only CPR, with the magnitude of difference attenuated and no longer statistically significant after statistical adjustments.
Study context
- Population
- Pediatric Out-of-hospital Cardiac Arrest (OHCA) patients in Japan, All-Japan Utstein Registry, 2011–2012
- Participants
- 2,157 patients
- Exposure
- Conventional cardiopulmonary resuscitation (CPR) vs compression-only CPR vs no-bystander CPR
- Conventionaln = 417
- Compression-onlyn = 733
- No-bystander CPRn = 1,007reference
- Outcome
- Favorable neurological state (Glasgow-Pittsburgh CPC 1–2, corresponding to Pediatric CPC 1–3)
- Follow-up
- 1 month after OHCA
Methodological detailspropensity-matched subset, multivariable logistic regression
- Propensity-matched subset
- Multivariable logistic regression
Main finding
As reported in the abstract
Favorable neurological state (CPC 1–2)
Estimate (95% CI)P value
Conventional vs Compression-onlyunadjusted
OR for neurologically favorable survival 3.42(2.45–4.76)
P < 0.0001Conventional vs Compression-onlymultivariable-adjusted; not statistically significant
adjusted OR for neurologically favorable survival 1.52(0.93–2.49)
Conventional vs Compression-onlypropensity-matched subset
OR for neurologically favorable survival 1.20(0.81–1.77)
Conventional vs No-bystander
adjusted OR for neurologically favorable survival 5.01(2.98–8.57)
Compression-only vs No-bystander
adjusted OR for neurologically favorable survival 3.29(1.93–5.71)
Observational data: associations, not effects.
Original publication
Conventional Versus Compression-Only Versus No-Bystander Cardiopulmonary Resuscitation for Pediatric Out-of-Hospital Cardiac Arrest. Circulation. Published 22 November 2016. doi:10.
Summarised from the published abstract; every number is checked against it