Coronary disease & ACSCohort study
Coronary Computed Tomographic Angiography With Fractional Flow Reserve in Patients With Type 2 Myocardial Infarction
- Prospective cohort study
- consecutive enrolment
Authors' conclusion
Among individuals with adjudicated T2MI, CAD was prevalent, but the majority of patients had nonobstructive CAD.
Study context
- Population
- Patients with T2MI (Fourth Universal Definition of MI) undergoing coronary computed tomography angiography (CTA), FFRCT and plaque volume analyses
- Participants
- 50 patients
- Outcome
- Presence and characteristics of CAD
Main finding
As reported in the abstract
Coronary plaque on CTA
46 (92%)
Moderate or greater stenosis (≥50%)
42%
Obstructive coronary artery disease (CAD) (≥50% left main or ≥70% other epicardial artery)
26%
Hemodynamically significant focal stenosis by FFRCT
13 (26%)
Observational data: associations, not effects.
Further findings
Obstructive CAD by T2MI cause
- Prevalence did not differ by T2MI cause
- P = 0.54
FFRCT in participants with stenosis ≥50% (n = 21)
- Lesion-specific hemodynamically significant stenosis excluded by FFRCT
- 8 (38%)
Original publication
Coronary Computed Tomographic Angiography With Fractional Flow Reserve in Patients With Type 2 Myocardial Infarction. J Am Coll Cardiol. Published 29 September 2023. doi:10.1016/j.jacc.2023.08.020
Summarised from the published abstract; every number is checked against it