Prevention & lipidsCross-sectional study

Coronary Plaque Volume in an Asymptomatic Population

JACC Cardiovasc ImagingPublished

  • Cross-sectional study
  • community-based cohort

Authors' conclusion

The large majority of study subjects had plaque detected by using AI-QCT.

Study context

Population
Asymptomatic adults without CVD in the MiHEART community-based cohort
Participants
2,301 adults
Exposure
Male vs Female
Outcome
Total coronary plaque volume by AI-guided quantitative coronary CT angiography (AI-QCT)

Main finding

As reported in the abstract

Total plaque volume

Total plaque volume

Total plaque volume ≥20 mm3 Male 81.5% · Female 61.9%

  • Male vs Female: P < 0.001

Observational data: associations, not effects.

Further findings

Total plaque volume by ethnicity · no difference

P = 0.756

Noncalcified plaque

Younger individuals had a greater percentage of noncalcified plaque

Original publication

Coronary Plaque Volume in an Asymptomatic Population. JACC Cardiovasc Imaging. Published 8 September 2025. doi:10.1016/j.jcmg.2025.08.001

Summarised from the published abstract; every number is checked against it