Coronary disease & ACSResearch article
Coronary sinus reducer implantation for refractory angina: a national audit of UK practice
- national audit
- Coronary sinus reducer (CSR) implanting centres in the UK
- structured collection template
Authors' conclusion
This national audit of real-world UK practice confirms CSR implantation is being performed appropriately and safely leading to symptom improvement for patients with refractory angina. Contemporary practice aligns with the recommendations of current guidelines supporting the continued use of CSR in UK clinical practice. Prospective data collection within a national registry is warranted.
Study context
- Population
- Patients undergoing clinical CSR implantation for refractory angina in the UK between November 2014 and 2024patients from 19 centres
- Participants
- 491 patients
Main finding
As reported in the abstract
Baseline characteristics
- Male
- 79%
- Previous myocardial infarction
- 75%
- Percutaneous coronary intervention
- 78%
- Coronary artery bypass grafting
- 69%
- Diabetes mellitus
- 53%
- Hypertension
- 76%
- Hypercholesterolaemia
- 78%
- Preserved LVEF (LVEF≥50%)
- 74%
- Canadian Cardiovascular Society (CCS) class ≥3 angina
- 84%
- ≥2 antianginal drugs
- 94%
- ≥3 antianginal drugs
- 74%
- Baseline ischaemia testing
- 79%
Further findings
Successful CSR implantation
- Successful CSR implantation
- 95%
Length of stay
- Stayed ≤1 night postprocedurally
- 98%
CCS class reduction · 6-month follow-up
- ≥1 CCS class angina reduction
- 75%
- ≥2 CCS class angina reduction
- 36%
- Significant reductions in CCS class
Angina status stratified by age, sex and diabetes mellitus
- Improved angina status was also observed after stratification by age, sex and diabetes mellitus
Safety
Periprocedural adverse events
- Periprocedural adverse events (AEs)
- 46
- Patients with periprocedural AEs
- 41
- Rate
- 9.2%
- Rates of major adverse cardiovascular events and severe AEs
- <1%
- most commonly due to access complications
Original publication
Coronary sinus reducer implantation for refractory angina: a national audit of UK practice. Heart. Published 26 May 2026. doi:10.1136/heartjnl-2025-327497
Summarised from the published abstract; every number is checked against it