Acute cardiac care & resuscitation
Cost-effectiveness analysis of a ‘Termination of Resuscitation’ protocol for the management of out-of-hospital cardiac arrest
Authors' conclusion
The application of the TOR protocol for the management of OHCA was found to be cost-effective within acceptable willingness-to-pay thresholds
Study context
- Population
- Out-of-hospital cardiac arrests (OHCA) cases eligible for the Termination of Resuscitation (TOR) protocol in Singaporemean age 73.0 ± 15.5 years
- Participants
- 3,695 cases
- Comparison
- TOR protocol vs No TOR
- Outcome
- Costs per QALY
- Follow-up
- 10-year time horizon
Methodological detailsMarkov model, healthcare provider's perspective, 10-year time horizon, probabilistic sensitivity analysis
- Markov model
- Healthcare provider's perspective
- 10-year time horizon
- Probabilistic sensitivity analysis
Main finding
As reported in the abstract
Cost per QALY
Savings per quality adjusted life years (QALY) loss
$400,440
Full TOR vs No TOR
Savings per QALY loss
$821,151
Full TOR vs Observed TOR
Full TOR
- Costs
- $19,633,369 (95% UI 19,469,973 to 19,796,764)
- QALYs
- 0
Full TOR
Costs$19,633,369 (95% UI 19,469,973 to 19,796,764)
QALYs0
Further findings
Events
| Outcome | No TOR | Observed TOR | Full TOR | |
|---|---|---|---|---|
| Additional deaths per 10,000 hypothetical patients vs No TORApproximately | Not reported in the abstract | 19 | 31 | No TOR: not reported in the abstract |
Original publication
Cost-effectiveness analysis of a ‘Termination of Resuscitation’ protocol for the management of out-of-hospital cardiac arrest. Resuscitation. Published 17 July 2024. doi:10.
Summarised from the published abstract; every number is checked against it