Arrhythmias & electrophysiologyMeta-analysis
Cost-effectiveness of an intraoperative antibacterial envelope in preventing cardiac implantable device-associated infections: a systematic review
- Systematic review of economic evaluations
- 142 unique citations screened
Authors' conclusion
Routine use of an antibacterial envelope in patients undergoing CIED procedures (implantation or revision) is unlikely to be cost-effective except among those at high risk for post-operative infection.
Study context
- Population
- Patients undergoing cardiac implantable electronic device (CIED) procedures (implantation or revision); economic evaluations from high-income countries, healthcare payer perspective
- Participants
- 7 studies
- Comparison
- Antibacterial envelope vs standard of care
- Outcome
- Cost-effectiveness (cost per quality-adjusted life year gained)
Pooled result
As reported in the abstract
Cost per quality-adjusted life year gained (base case)
Base case cost per QALY exceeded country-specific thresholds for good value
5/7
May be cost-effective at base infection rates greater than
3%
Cost-saving at infection rates exceeding
6%
Original publication
Cost-effectiveness of an intraoperative antibacterial envelope in preventing cardiac implantable device-associated infections: a systematic review. Europace. Published 16 June 2025. doi:10.1093/europace/euaf121
Summarised from the published abstract; every number is checked against it