Coronary disease & ACSCohort study

Cost-Effectiveness of Early Discharge (<48 Hours) for Low-Risk Patients Following PPCI for STEMI

JACC Cardiovasc IntervPublished

  • Cohort study

Authors' conclusion

Selected low-risk patients can be discharged securely and safely following successful primary percutaneous coronary intervention using a pathway that is reinforced by a formal, multidisciplinary virtual follow-up program, enabling improvements in medication adherence and up-titration.

Study context

Population
Low-risk patients after primary PCI for STEMI, April 2020–March 2023
Participants
1,500 vs 1,400
Exposure
Early discharge with virtual follow-up vs >48-hour discharge
  • Early dischargen = 1,500
  • >48-hour controln = 1,400reference

Main finding

As reported in the abstract

MACE · 12 months

P = 0.043

Observational data: associations, not effects.

Further findings

Length of hospital stay

Median length of stay, early discharge pathway (min 17 h, max 40 h)
24.9 hours (Q1-Q3: 22.8-36.4 hours)
Median length of stay, control
68.1 hours (Q1-Q3: 56-80 hours) (P < 0.0001)
Stayed 1 fewer night in hospital vs normal pathways
73% (1,095 of 1,500)

Original publication

Cost-Effectiveness of Early Discharge (&lt;48 Hours) for Low-Risk Patients Following PPCI for STEMI. JACC Cardiovasc Interv. Published 23 June 2025. doi:10.1016/j.jcin.2025.04.045

Summarised from the published abstract; every number is checked against it