Valvular & structural heart diseaseCohort study
CT and Fluoroscopic Analyses of Valve Expansion in Redo-TAVR
- Observational imaging study
- first-in-human
- consecutive patients
Index transcatheter aortic valve (TAVs) predilated in 80% (24 of 30); both TAVs postdilated in all cases
Authors' conclusion
There was significant underexpansion of both index and second TAVs after redo-TAVR, irrespective of valve type and combinations.
Study context
- Population
- Patients undergoing redo-TAVR for bioprosthetic valve failure, January 2023 to April 2025of 40 consecutive
- Participants
- 30 patients
- Exposure
- Short-in-short vs Short-in-tall vs Tall-in-short
- Short-in-shortn = 8
- Short-in-talln = 16
- Tall-in-shortn = 6
- Outcome
- Frame expansion and geometry of index and second TAVs by multidetector computed tomography (MDCT) and fluoroscopy
Main finding
As reported in the abstract
Valve frame expansion (MDCT and fluoroscopy)
- Index TAVs all underexpanded; expansion seen after redo-TAVR in all cases
- Second TAVs underexpanded across all valve types, more so with tall-in-short (Evolut-in-SAPIEN)
Observational data: associations, not effects.
Further findings
Valve gradients and hypoattenuated leaflet thickening · 30 days
- No elevated valve gradients and no hypoattenuated leaflet thickening
Original publication
CT and Fluoroscopic Analyses of Valve Expansion in Redo-TAVR. JACC Cardiovasc Interv. Published 26 June 2025. doi:10.1016/j.jcin.2025.06.017
Summarised from the published abstract; every number is checked against it