Prevention & lipidsRandomised controlled trial
Culturally Adapted Lifestyle Intervention for South Asian Adults With Cardiovascular Risk Factors
- Randomised controlled trial
- single-blind
- community sites
- Conducted March 6, 2018, to February 11, 2023
Authors' conclusion
In the SAHELI randomized clinical trial, a culturally adapted, group lifestyle intervention was not more effective than written health education materials for CVD risk factor reduction among US South Asian adults, but the intervention was associated with small improvements in self-reported health behaviors.
Study context
- Population
- US South Asian adults aged 18–65 y, overweight or obese, no prior cardiovascular disease (CVD) events, ≥1 additional CVD risk factor (hypertension, dyslipidemia, prediabetes or diabetes); Chicago metropolitan arearandomized
- Participants
- 549 adults
- Comparison
- Intervention vs Control
- Primary endpoint
- Between-group differences in CVD risk factor changes (weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), HbA1c, total cholesterol)
- Follow-up
- Baseline to 12 months
Primary result
As reported in the abstract
CVD risk factor change, intervention vs control · 12 months
Intervention vs ControlMean difference, kg (95% CI)
weight
−0.07(−0.55 to 0.42)
Intervention vs ControlMean difference, mm Hg (95% CI)
SBP
0.47(−1.85 to 2.79)
DBP
0.44(−1.06 to 1.95)
Intervention vs ControlMean difference, mg/dL (95% CI)
cholesterol
−2.47(−8.51 to 3.57)
Intervention vs ControlMean difference, % (95% CI)
HbA1c
−0.07(−0.20% to 0.07%)
Secondary outcomes
Self-reported diet quality, physical activity (PA), self-efficacy
- Greater improvements in dietary quality, PA and self-efficacy with intervention than control
Original publication
Culturally Adapted Lifestyle Intervention for South Asian Adults With Cardiovascular Risk Factors. JAMA Cardiol. Published 1 November 2024. doi:10.1001/jamacardio.2024.2526
Summarised from the published abstract; every number is checked against it