Heart failure & cardiomyopathies

Current epidemiology and management of acute heart failure: the multicenter prospective OFICA2 cohort

Eur Heart J Qual Care Clin OutcomesPublished French prospective multicenter cohort

Authors' conclusion

This comprehensive survey about patients hospitalized with AHF emphasizes HF care pathway, medical therapies and follow-up as weak spots. Filling these gaps might improve patients’ management and prognosis.

Study context

Population
Patients hospitalized for acute heart failure (AHF) in France, March to April 2021consecutive patients hospitalized for AHF (mean age 76 years, 61% male)
Participants
1,513 patients
Outcome
Admission ward
Methodological details80 participating centres, consecutive patients
  • 80 participating centres
  • Consecutive patients

Main finding

As reported in the abstract

Not admitted in cardiology wards
One in five patients

Observational data: associations, not effects.

Further findings

Triggering factor

Triggering factor identified
70%
Supraventricular arrhythmia
21%

Hospital stay and in-hospital mortality

Median hospital stay
11 days
In-hospital mortality
4.6%

Predictors of in-hospital outcomes (composite of all-cause death, cardiogenic shock or transfer to intensive care unit)

Predictive factors of worse outcomes: younger age, initial acute coronary syndrome, ventricular arrhythmia, left ventricular ejection fraction (LVEF) ≤ 40%, lower systolic blood pressure, worse kidney function, higher C-reactive protein level on admission

Management at discharge

Appointment scheduled with a cardiologist
61%
Patients with LVEF ≤ 40% with beta-blocker, renin-angiotensin system blocker and mineralocorticoid receptor antagonist
1 out of 4
No HF medication
12%

Original publication

Current epidemiology and management of acute heart failure: the multicenter prospective OFICA2 cohort. Eur Heart J Qual Care Clin Outcomes. Published 20 June 2025. doi:10.1093/ehjqcco/qcaf044

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