Heart failure & cardiomyopathies
Current epidemiology and management of acute heart failure: the multicenter prospective OFICA2 cohort
Authors' conclusion
This comprehensive survey about patients hospitalized with AHF emphasizes HF care pathway, medical therapies and follow-up as weak spots. Filling these gaps might improve patients’ management and prognosis.
Study context
- Population
- Patients hospitalized for acute heart failure (AHF) in France, March to April 2021consecutive patients hospitalized for AHF (mean age 76 years, 61% male)
- Participants
- 1,513 patients
- Outcome
- Admission ward
Methodological details80 participating centres, consecutive patients
- 80 participating centres
- Consecutive patients
Main finding
As reported in the abstract
- Not admitted in cardiology wards
- One in five patients
Observational data: associations, not effects.
Further findings
Triggering factor
- Triggering factor identified
- 70%
- Supraventricular arrhythmia
- 21%
Hospital stay and in-hospital mortality
- Median hospital stay
- 11 days
- In-hospital mortality
- 4.6%
Predictors of in-hospital outcomes (composite of all-cause death, cardiogenic shock or transfer to intensive care unit)
- Predictive factors of worse outcomes: younger age, initial acute coronary syndrome, ventricular arrhythmia, left ventricular ejection fraction (LVEF) ≤ 40%, lower systolic blood pressure, worse kidney function, higher C-reactive protein level on admission
Management at discharge
- Appointment scheduled with a cardiologist
- 61%
- Patients with LVEF ≤ 40% with beta-blocker, renin-angiotensin system blocker and mineralocorticoid receptor antagonist
- 1 out of 4
- No HF medication
- 12%
Original publication
Current epidemiology and management of acute heart failure: the multicenter prospective OFICA2 cohort. Eur Heart J Qual Care Clin Outcomes. Published 20 June 2025. doi:10. 1093/ ehjqcco/ qcaf044
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