Valvular & structural heart disease

Decompression Illness in Divers With or Without Patent Foramen Ovale : A Cohort Study

Ann Intern MedPublished Prospective cohort study

Main finding · PFO-related DCIResult — go to the resultOdds ratio 9.34 95% CI 1.95–44.88

Authors' conclusion

High-risk PFO was associated with an increased risk for DCI in scuba divers.

Study context

Population
Experienced scuba divers (>50 dives/year) from 13 diving organizations, tertiary cardiac centre, South Korea68 with PFO
Participants
100 participants
Exposure
High-risk PFO vs low-risk PFO vs no PFO
  • High-risk PFOn = 37
  • Low-risk PFOn = 31
Outcome
PFO-related DCI
Follow-up
Mean 28.7 months
Methodological detailssingle-centre, TEE with saline bubble test; participants blinded to PFO status; symptoms adjudicated blinded
  • Single-centre
  • TEE with saline bubble test; participants blinded to PFO status; symptoms adjudicated blinded

Main finding

As reported in the abstract

Odds ratio

9.34

95% CI 1.95–44.88

By group

High-risk PFOvs Non-PFO
OR 9.34 (95% CI 1.95–44.88)
PFO-related decompression illness (DCI) in PFO divers
12
Difference across groups
P = 0.001

Observational data: associations, not effects.

Original publication

Decompression Illness in Divers With or Without Patent Foramen Ovale : A Cohort Study. Ann Intern Med. Published 11 July 2023. doi:10.7326/m23-0260

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