deliVERy of optimal blood pressure coNtrol in afrICA (VERONICA)-Nigeria study: Rationale and design of a randomized clinical trial
Study context
- Population
- Black African adults with uncontrolled hypertension, untreated or on monotherapy, Nigeriaplanned
- Participants
- 300 adults
- Planned comparison
- Triple pill-based treatment protocol vs Nigeria hypertension treatment protocol (standard care)
- Primary endpoint
- Change in home mean SBP from baseline
- Follow-up
- Month 6
Methodological detailsrationale and design, parallel-group, open-label, 1:1 randomisation, noncomparative 12-month extension, Economic and process evaluations planned, Key secondary outcome: % with clinic blood pressure (BP) <140/90 mmHg at month 6, Primary safety outcome: discontinuation due to adverse events to month 6
- Rationale and design
- Parallel-group
- Open-label
- 1:1 randomisation
- Noncomparative 12-month extension
- Economic and process evaluations planned
- Key secondary outcome: % with clinic BP <140/90 mmHg at month 6
- Primary safety outcome: discontinuation due to adverse events to month 6
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
deliVERy of optimal blood pressure coNtrol in afrICA (VERONICA)-Nigeria study: Rationale and design of a randomized clinical trial. Am Heart J. Published 31 July 2024. doi:10.
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