Heart failure & cardiomyopathiesTrial design
Design, Characteristics, and Implementation of the Financial Support for Low-Income Patients with Heart Failure Trial
- pilot randomized controlled trial
- 1:1 randomization within 14 days of discharge
Study context
- Population
- Adults hospitalized for acute heart failure (HF) with reduced ejection fraction with income <130% federal poverty limit and difficulty paying bills with ≥1 additional socioeconomic needrandomized participants, 140 completed 1-month follow-up · financial support 76 · control 77
- Participants
- 153 adults
- Planned comparison
- early financial support vs control
- financial supportn = 76
- controln = 77
No results yet. This paper sets out the design of a trial; its results are to come.
Baseline
Baseline characteristics
- mean age
- 53 y
- male
- 76%
- Black
- 73%
- mean ejection fraction
- 26 ± 9%
- median monthly income
- $600 (IQR 0-1179)
- cost-related medication non-adherence at baseline
- 76%
- identified socioeconomic domain needs, on average
- 5
- housing instability
- 50%
- food insecurity
- 85%
- transportation barriers
- 65%
- unemployed or retired
- 81%
- Baseline characteristics well balanced between groups except for numerically higher median monthly income and lower mineralocorticoid receptor antagonist/sodium-glucose cotransporter-2 inhibitor prescription in the financial support group
- The primary clinical outcomes are reported in a companion Brief Report.
Follow-up completeness · 1 month
- completed 1-month follow-up
- 140
Original publication
Design, Characteristics, and Implementation of the Financial Support for Low-Income Patients with Heart Failure Trial. JACC Adv. Published 16 March 2026. doi:10.1016/j.jacadv.2026.102698
Summarised from the published abstract; every number is checked against it