Coronary disease & ACSDiagnostic or prognostic study
Detecting Hemorrhagic Myocardial Infarction With 3.0-T Cardiac Magnetic Resonance (CMR)
- Diagnostic accuracy study
- animal model
- time-lapse multiparametric mapping
- 3.0-T CMR
Authors' conclusion
HMI cannot be reliably detected with T1, T2, or T2∗ on 3.0-T CMR immediately after reperfusion. However, T2∗ CMR can be used to diagnose hMI between 24 hours and 7 days postreperfusion. T2 maps at 3.0-T are a strong alternative to T2∗ maps for diagnosing hMI, provided CMR is performed 5 to 7 days postreperfusion. However, diagnosing hMI with T1 is significantly more challenging at 3.0-T compared with both T2∗ and T2.
Study context
- Population
- Canines with reperfused MI; reperfused STEMI patients to establish clinical feasibility20 canines · 50 STEMI patients
- Comparison
- T1, T2 and T2∗ mapping on 3.0-T CMR for detection of hemorrhagic myocardial infarction (hMI)
Performance
As reported in the abstract
Detection of hMI
| Test or model | T2∗ baseline | T2∗ hMI | AUC vs T2∗ (5 to 7 days) | Sensitivity and specificity | Sensitivity (all time points) |
|---|---|---|---|---|---|
| T2∗ | 27.0 ± 2.4 ms | 11.7 ± 2.8 ms | |||
| T2 | 0.98 | ≥0.95 | |||
| T1 | <0.8 |
- T2∗ hMI vs T2∗ baseline: P < 0.001 — 24 hours to 7 days postreperfusion
Original publication
Detecting Hemorrhagic Myocardial Infarction With 3.0-T CMR. JACC Cardiovasc Imaging. Published 8 January 2025. doi:10.1016/j.jcmg.2024.10.006
Summarised from the published abstract; every number is checked against it