Heart failure & cardiomyopathiesResearch article
Determinants of exercise performance in heart failure patients with extremely reduced cardiac output and left ventricular assist device
- Narrative literature review
Authors' conclusion
The present paper confirms the role of CPET in the follow-up of this peculiar population and the impact of exercise capacity on the quality of life of AdHF patients.
Study context
- Population
- Patients with advanced HF (advanced heart failure (AdHF)), including left ventricular assist device (LVAD) recipients
Main finding
As reported in the abstract
Determinants of exercise limitation in AdHF and LVAD recipients (narrative literature review)
- Exercise intolerance is multifactorial: central and peripheral haemodynamic regulation, anaemia and iron deficiency, pulmonary congestion, pulmonary hypertension, peripheral O2 extraction
- Possible interventions to increase exercise capacity: levosimendan, rehabilitation, LVAD speed changes
- Role of CPET in follow-up confirmed; exercise capacity affects quality of life in AdHF
Original publication
Determinants of exercise performance in heart failure patients with extremely reduced cardiac output and left ventricular assist device. Eur J Prev Cardiol. Published 11 October 2023. doi:10.1093/eurjpc/zwad239
Summarised from the published abstract; every number is checked against it