Acute cardiac care & resuscitation

Development of the CASPER-Score: A bedside tool integrating artificial intelligence (AI)-based electrocardiogram (ECG) analysis with key clinical predictors to identify relevant coronary artery stenosis in patients after out-of-hospital cardiac arrest

ResuscitationPublished

  • single-center, retrospective, cohort study

Authors' conclusion

The CASPER-Score may improve early risk stratification and support decision-making regarding coronary angiography in OHCA patients.

Study context

Population
OHCA patients admitted to the intensive care unit between 01/2019 and 12/2021 who underwent coronary angiography within seven daysOHCA patients undergoing coronary angiography within 7 days
Participants
204 patients
Exposure
CASPER-Score for relevant coronary artery stenosis
Outcome
Relevant coronary artery stenosis (≥50% diameter stenosis of the left main coronary artery or ≥70% of all other vessels)

Main finding

As reported in the abstract

Relevant coronary artery stenosis present

157 patients (77%)

CASPER-Score range

0-8 points

CASPER-Score discrimination (good)

AUC = 0.86

Observational data: associations, not effects.

Secondary outcomes

Coronary revascularization (secondary outcome)

Underwent coronary revascularization
127 patients (62.3%)
Model predicting revascularization discrimination (moderate)
AUC = 0.74

Original publication

Development of the CASPER-Score: A bedside tool integrating AI-based ECG analysis with key clinical predictors to identify relevant coronary artery stenosis in patients after out-of-hospital cardiac arrest. Resuscitation. Published 7 July 2026. doi:10.1016/j.resuscitation.2026.111198

Summarised from the published abstract; every number is checked against it