Prevention & lipids

Diagnosing chronotropic incompetence: a scoping review of current approaches and their application in a cardiac rehabilitation cohort

Eur J Prev CardiolPublished Scoping review with retrospective cohort study

Authors' conclusion

Current methods to define CI and predict APMHR are inconsistent and problematic.

Study context

Population
Published studies defining chronotropic incompetence; patients in a cardiac rehabilitation program
Participants
86 studies
Exposure
Definitions of chronotropic incompetence and age-predicted maximal heart rate (APMHR) prediction formulas
Outcome
Definitions of chronotropic incompetence and APMHR prediction formulas identified

Main finding

As reported in the abstract

Studies included

86

Distinct methods to define chronotropic incompetence

17

Observational data: associations, not effects.

Original publication

Diagnosing chronotropic incompetence: a scoping review of current approaches and their application in a cardiac rehabilitation cohort. Eur J Prev Cardiol. Published 5 May 2026. doi:10.1093/eurjpc/zwag253

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