Prevention & lipidsCohort study

Dietary carbohydrate quality, fibre-rich food intake, and left ventricular structure and function: the CARDIA study

Eur Heart JPublished

  • Prospective cohort study

Authors' conclusion

Higher quality of CHO and intake of fibre-rich foods were favourably associated with LV structure and function.

Study context

Population
CARDIA participants; diet at exam years 0, 7 and 20, echocardiography at years 25 and 30
Participants
3,171 participants
Exposure
Quartiles of CHO quality and of fibre-rich food score
Outcome
Cardiac phenotype measures (LV structure and function) by echocardiography
Follow-up
Exam years 25 and 30

Main finding

As reported in the abstract

Cardiac phenotypes across quartiles
CHO quality quartiles favourably associated with left ventricular (LV) mass index
Ptrend < .001
CHO quality quartiles favourably associated with global longitudinal strain
Ptrend < .001
Fibre-rich food score quartiles favourably associated with LV mass index
Ptrend < .001
Fibre-rich food score quartiles favourably associated with LVEF
Ptrend = .008
Fibre-rich food score quartiles favourably associated with global longitudinal strain
Ptrend < .001
Fibre-rich food score quartiles favourably associated with E/e' ratio
Ptrend = .02
Fibre-rich food score quartiles favourably associated with left atrial volume index
Ptrend = .02
Effect sizes as % of respective SDs
between 10% and 26%

Observational data: associations, not effects.

Original publication

Dietary carbohydrate quality, fibre-rich food intake, and left ventricular structure and function: the CARDIA study. Eur Heart J. Published 8 July 2025. doi:10.1093/eurheartj/ehaf406

Summarised from the published abstract; every number is checked against it