Coronary disease & ACSRandomised controlled trial
Digital Cognitive Behavioral Therapy for Cardiac Anxiety After Myocardial Infarction
- randomized clinical trial
Authors' conclusion
A therapist-guided, digitally delivered CBT intervention targeting cardiac anxiety improved disease-specific health status and reduced cardiac anxiety after MI, with durable effects. These findings support the clinical relevance of integrating psychological interventions into multidisciplinary secondary prevention after MI. (Online Cognitive Behavioral Therapy Targeting Cardiac Anxiety [MI-CBT]; NCT05580718).
Study context
- Population
- Patients with a history of type 1 myocardial infarction (MI) (≥6 months prior) and clinically significant cardiac anxiety
- Comparison
- digital CA-CBT or usual care
- Primary endpoint
- Disease-specific health status (Seattle Angina Questionnaire)
- Follow-up
- 3-month follow-up
Primary result
As reported in the abstract
- Compared with usual care, CA-CBT was associated with greater improvements in disease-specific health status, particularly quality of life and physical limitation
Further findings
Cardiac anxiety
- Greater reductions in cardiac anxiety with CA-CBT compared with usual care
Durability of treatment effects · 12 months
- Treatment effects were sustained at 12 months
Original publication
Digital Cognitive Behavioral Therapy for Cardiac Anxiety After Myocardial Infarction. JACC Adv. Published 25 March 2026. doi:10.1016/j.jacadv.2026.102669
Summarised from the published abstract; every number is checked against it