Heart failure & cardiomyopathiesCohort study
Disparities in donor heart acceptance between the USA and Europe: clinical implications
- Retrospective cohort study
- registry comparison
Authors' conclusion
Eurotransplant countries exhibit more liberal donor heart acceptance practices than the USA.
Study context
- Population
- Adult reported heart donors, 2010–2020
- Participants
- 8,714 vs 60,882
- Exposure
- Eurotransplant vs USA donor heart acceptance
- Eurotransplantn = 8,714
- USAn = 60,882reference
- Outcome
- Donor utilization (percentage of reported donors accepted for HT)
Main finding
As reported in the abstract
Donor utilization
Observational data: associations, not effects.
Further findings
Predictors of donor non-acceptance
- Donor age, smoking history and DM predicted non-acceptance in the USA and, by a lesser magnitude, in Eurotransplant
- Donor obesity and hypertension predicted non-acceptance in the USA only
Estimated additional US heart transplant (HTs) with Eurotransplant-level utilization among top 30%-50% of donors (by quality) · annually
- Additional US HTs annually
- 506-930
Original publication
Disparities in donor heart acceptance between the USA and Europe: clinical implications. Eur Heart J. Published 4 November 2023. doi:10.1093/eurheartj/ehad684
Summarised from the published abstract; every number is checked against it