Cohort study
Distal Target Vessel Quality and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention
- Retrospective cohort study
- multicentre
Authors' conclusion
A poor-quality distal vessel in CTO lesions is associated with higher lesion complexity, higher need for retrograde crossing, lower technical and procedural success, higher incidence of MACE and coronary perforation, and higher radiation dose.
Study context
- Population
- Chronic total occlusion (CTO) PCIs at 39 US and non-US centres, 2012–2022
- Participants
- 10,028 CTO PCIs
- Exposure
- Poor-quality vs good-quality distal vessel in CTO PCI
Main finding
As reported in the abstract
Technical success, procedural success and in-hospital MACE
Technical success
P < 0.01
Procedural success
P < 0.01
In-hospital MACE
- Poor-quality distal vessel vs Good-quality distal vessel: P < 0.01 — major adverse cardiac events (MACE)
Observational data: associations, not effects.
Further findings
Use of retrograde approach
P < 0.01
| Outcome | Poor-quality distal vessel | Good-quality distal vessel | P value |
|---|---|---|---|
| J-CTO score | 2.7 ± 1.1 | 2.2 ± 1.3 | P < 0.01 |
Safety
Perforation
P < 0.01
Air kerma radiation dose
P < 0.01
Original publication
Distal Target Vessel Quality and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention. JACC Cardiovasc Interv. Published 26 June 2023. doi:10.1016/j.jcin.2023.03.007
Summarised from the published abstract; every number is checked against it