Arrhythmias & electrophysiologyMechanistic study
Diverse QRS morphology reflecting variations in lead placement for left bundle branch area pacing
- Mechanistic study
Authors' conclusion
Different QRS morphologies and axes were linked to the location of the non-selective LBBAP lead in the septum. Various lead deployments are feasible for LBBAP, allowing diversity in the conduction system capture in patients with atrioventricular block.
Study context
- Population
- Patients with atrioventricular block
- Participants
- 50 vs 21
- Comparison
- Non-selective left bundle branch area pacing (LBBAP) vs LVSP; lead location in the septum
- Non-selective LBBAPn = 50
- LVSPn = 21reference
- Outcome
- Impact of septal lead location on QRS morphology during non-selective LBBAP
Main finding
As reported in the abstract
QRS morphology and lead location
qR-wave in V1 indicated inferior septum as primary lead location
93%
Further findings
Penetration depth of non-selective LBBAP lead, anterior vs inferior septum
Penetration depth of non-selective LBBAP lead, anterior vs inferior septum
- Significantly shallower in the anterior septum
Original publication
Diverse QRS morphology reflecting variations in lead placement for left bundle branch area pacing. Europace. Published 25 September 2023. doi:10.1093/europace/euad241
Summarised from the published abstract; every number is checked against it