Pulmonary vascular disease & thromboembolism
Do we have our FACTTs straight about cor pulmonale in acute respiratory distress syndrome?
Authors' conclusion
While the FACTT data demonstrate neither a clear nor a consistent relationship between right ventricular-pulmonary arterial function and traditional risk factors, this does not indicate their unimportance.
Study context
- Population
- Patients with acute respiratory distress syndrome
- Primary endpoint
- Association of traditional cor pulmonale risk factors (pH, PaO2:FiO2, PaCO2, driving pressure) and PEEP with cor pulmonale parameters (Cpa, PVRi, PAPi, Ea)
Primary result
As reported in the abstract
Cor pulmonale parameters and their associations with risk factors · Day 1
Median (IQR) compliance (Cpa), mL/mmHg
4.28
3.14, 6.08
Median (IQR) elastance (Ea), mmHg/mL
0.48
0.36, 0.66
Median (IQR) pulmonary artery pulsatility index (PAPi)
1.58
1.13, 2.38
Median (IQR) pulmonary vascular resistance index (PVRi), WU*m²
3.86
2.45, 4.79
Original publication
Do we have our FACTTs straight about cor pulmonale in acute respiratory distress syndrome? Eur Heart J Acute Cardiovasc Care. Published 12 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →