Does adding a delayed phase to cardiac computed tomography for coronary artery evaluation have prognostic value?
Authors' conclusion
In patients undergoing CCT for coronary artery evaluation, coexistence of LIE and elevated ECV is associated with higher risk of cardiovascular events and their assessment may provide synergistic prognostic value.
Study context
- Population
- Patients undergoing cardiac computed tomography (CCT) for coronary artery assessment, January 2020 to September 2022Of 1305 patients, 1207 met inclusion criteria, mean follow-up 26.0 ± 19.1 months
- Participants
- 1,207 patients
- Exposure
- Four groups based on the presence of late iodine enhancement (LIE) and elevated ECV
- Outcome
- Composite of:
- All-cause death
- Unplanned cardiovascular hospitalizations
- Follow-up
- Mean 26.0 ± 19.1 months
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Stepwise increase in risk across the four groups; highest cumulative incidence of composite events with LIE and elevated ECV
log-rank P = 0.027
LIE and elevated ECV group, HR for the composite outcome
1.84, 95% CI 1.22-2.79
Observational data: associations, not effects.
Secondary outcomes
Cardiovascular events (cardiac death and unplanned cardiovascular hospitalization) (secondary outcome)
- LIE and elevated ECV group, HR for cardiovascular events
- 2.67, 95% CI 1.32-5.41
- Comparator group of the HR not stated
Original publication
Does adding a delayed phase to cardiac computed tomography for coronary artery evaluation have prognostic value? Eur Heart J Cardiovasc Imaging. Published 22 January 2026. doi:10.
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