Arrhythmias & electrophysiologyResearch article
Double potential gradient analysis for critical isthmus detection in scar-related atrial tachycardia
- Double potential gradient analysis
Authors' conclusion
DP gradient is a more accurate predictor of isthmus points than DP duration, and may be useful in identifying its location.
Study context
- Population
- Patients undergoing ablation of scar-mediated atrial tachycardia (AT) with a complete high-density map available57 EAMs among 52 patients, 13 (25.0%) female, median age 69.1 years
- Participants
- 52 patients
- Comparison
- DP duration gradient compared with DP duration as a quantitative metric in isthmus identification
Main finding
As reported in the abstract
DP gradient values, isthmus vs nonisthmus points
- Isthmus points vs Nonisthmus points: P < 0.001
- Pooled isthmus points
Further findings
Area under the curve
| Outcome | DP gradient | DP duration | P value |
|---|---|---|---|
| Prediction of isthmus location (logistic regression), DP gradient vs DP duration · DP gradient more predictive of isthmus location | 0.667 (95% CI 0.660–0.673) | 0.621 (95% CI 0.616–0.627) | P < 0.001 |
Original publication
Double potential gradient analysis for critical isthmus detection in scar-related atrial tachycardia. Heart Rhythm. Published 15 April 2026. doi:10.1016/j.hrthm.2026.04.007
Summarised from the published abstract; every number is checked against it