Valvular & structural heart disease
Routine post-dilatation at nominal volume to optimise the expansion of balloon-expandable valves: the DOUBLE-TAP study
Authors' conclusion
In favourable anatomy, routine double-tap after BE TAVI improved THV expansion with no safety concerns.
Study context
- Population
- Patients undergoing transcatheter aortic valve implantation (TAVI) with the SAPIEN 3 Ultra (S3U) valve, excluding severe annular or subannular calcification
- Participants
- 102 patients
- Exposure
- Before vs after routine double-tap post-dilatation
- Outcome
- Increase in minimal THV expansion by cross-sectional area after double-tap, by valve size
Main finding
As reported in the abstract
20 mm S3U (p=0.151)
9.8%
23 mm S3U (p<0.001)
9.9%
26 mm S3U (p<0.001)
9.2%
29 mm S3U (p=0.002)
8.6%
Observational data: associations, not effects.
Further findings
THV underexpansion after first inflation
- All patients had some degree of THV underexpansion after the first inflation, despite nominal deployment
Stroke and CV mortality · 30 days
- No stroke or CV mortality
Original publication
Routine post-dilatation at nominal volume to optimise the expansion of balloon-expandable valves: the DOUBLE-TAP study. EuroIntervention. Published 6 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →