Valvular & structural heart diseaseMeta-analysis
Durability of Mitral Valve Transcatheter Edge-to-Edge Repair
- Systematic review and meta-analysis
Authors' conclusion
The incidence of M-TEER failure after a successful index procedure increases after 3 years and is more pronounced with primary than secondary MR.
Study context
- Population
- Patients treated with mitral transcatheter edge-to-edge repair (M-TEER) for mitral regurgitation (MR)33 papers
- Comparison
- Primary MR vs Secondary MR
- Outcome
- M-TEER durability: MR recurrence, reintervention and their composite (weighted means)
Pooled result
As reported in the abstract
MR recurrence and reintervention (pooled weighted means)
MR recurrence and reintervention in first months after index procedure
between 5% and 10%
MR recurrence at 5 years
17%
Reintervention at 5 years
9%
Further pooled results
| Outcome | Primary MR | Secondary MR |
|---|---|---|
| MR recurrence or reintervention, primary vs secondary MR · 5 years | 41% | Not reported in the abstract |
MR recurrence or reintervention, primary vs secondary MR · 5 years
- Numerically higher in primary than secondary MR
Treatment of M-TEER failure
- Redo TEER seemed safer than surgery; 1-year MR recurrence
- between 20% and 40%
- Mitral valve replacement the most common surgical technique
Original publication
Durability of Mitral Valve Transcatheter Edge-to-Edge Repair. JACC Cardiovasc Interv. Published 16 March 2026. doi:10.1016/j.jcin.2026.02.019
Summarised from the published abstract; every number is checked against it