Arrhythmias & electrophysiology
Durability of output-dependent QRS transition and left bundle branch capture in left bundle branch area pacing
Authors' conclusion
Output-dependent QRS transitions were highly reproducible after implantation. Furthermore, LBB thresholds remained stable in most cases during the first postoperative year.
Study context
- Population
- Patients with successful left bundle branch area pacing (LBBAP) available for 1-year follow-up
- Participants
- 129 patients
- Exposure
- QRS transition on POD-0 vs No QRS transition on POD-0
- QRS transition on POD-0n = 73
- No QRS transition on POD-0n = 56
- Outcome
- Presence of output-dependent QRS transition and capture thresholds of the LBB and LV septal myocardium
- Follow-up
- Immediately and up to 1 year after LBBAP
Methodological detailsThreshold testing on POD-0, POD-3, POD-180 and POD-360
- Threshold testing on POD-0, POD-3, POD-180 and POD-360
Main finding
As reported in the abstract
Output-dependent QRS transition on POD-360 · POD-360
| Group | Value | QRS transition persisted | No QRS transition thereafter |
|---|---|---|---|
| QRS transition on POD-0 | 88% | 64 (88%) | |
| No QRS transition on POD-0 | 98% | 55 of 56 (98%) |
Value
QRS transition on POD-088%
No QRS transition on POD-098%
QRS transition persisted
QRS transition on POD-064 (88%)
No QRS transition on POD-0Not reported in the abstract
No QRS transition thereafter
QRS transition on POD-0Not reported in the abstract
No QRS transition on POD-055 of 56 (98%)
- Left bundle branch (LBB) thresholds POD-0 vs POD-360 (at 0.4 ms), slightly elevated, not significant
- 1.22 ± 1.00 V vs 1.43 ± 1.29 V; P = .26
- LBB threshold increased by ≥1.5 V
- 7 patients (11%)
- LBB capture maintained at 2.5 V on POD-360 in patients with LBB threshold ≤2.5 V on POD-0
- 93%
- LV septal thresholds POD-0 vs POD-360, similar
- 0.81 ± 0.36 V vs 0.83 ± 0.24 V; P > .99
- LV septal threshold increased by ≥1.5 V
- 0
Observational data: associations, not effects.
Original publication
Durability of output-dependent QRS transition and left bundle branch capture in left bundle branch area pacing. Heart Rhythm. Published 22 August 2024. doi:10.
Summarised from the published abstract; every number is checked against it