Acute cardiac care & resuscitationCohort study
Duration of cardiopulmonary resuscitation and outcomes for adults with in-hospital cardiac arrest: retrospective cohort study
- Retrospective cohort study
- multicentre registry
Authors' conclusion
This analysis of a large multicenter registry of in-hospital cardiac arrest quantified the time dependent probabilities of patients' outcomes in each minute of duration of cardiopulmonary resuscitation.
Study context
- Population
- Adults (≥18 years) with index in-hospital cardiac arrest receiving CPR, US multicentre registry, 2000–2021
- Participants
- 348,996 adults
- Outcome
- Survival to hospital discharge and favourable functional outcome (cerebral performance category 1 or 2) at discharge; time dependent probabilities by minute of CPR duration
- Follow-up
- Hospital discharge
Main finding
As reported in the abstract
Time dependent probabilities among patients pending ROSC
Survival at 1 minute of CPR (75 645/343 866)
22.0%
Favourable functional outcome at 1 minute of CPR (49 769/328 771)
15.1%
Observational data: associations, not effects.
Further findings
Return of spontaneous circulation and CPR duration
- Achieved ROSC: 233 551; median start of chest compressions to ROSC 7 (IQR 3-13) minutes
- 66.9%
- No ROSC: 115 445; median start of chest compressions to termination 20 (14-30) minutes
- 33.1%
Survival to hospital discharge (overall)
- 78 799 survived to discharge
- 22.6%
Original publication
Duration of cardiopulmonary resuscitation and outcomes for adults with in-hospital cardiac arrest: retrospective cohort study. BMJ. Published 7 February 2024. doi:10.1136/bmj-2023-076019
Summarised from the published abstract; every number is checked against it