Heart failure & cardiomyopathies
Dynamic changes in nocturnal heart rate predict short-term cardiovascular events in patients using the wearable cardioverter-defibrillator: from the WEARIT-France cohort study
Main findingResult — go to the resultAdjusted hazard ratio 6.08 95% CI 2.56–14.45Authors' conclusion
Dynamic monitoring of NHR may allow timely identification of impending cardiovascular events, with the potential for 'pre-emptive' action.
Study context
- Population
- HF patients using a wearable cardioverter-defibrillator (WCD), 2014–2018
- Participants
- 1,013 patients
- Exposure
- Nocturnal heart rate (NHR) trajectory categories
- Outcome
- Composite of:
- CV death
- HF hospitalization
Main finding
As reported in the abstract
Adjusted hazard ratio
6.08
95% CI 2.56–14.45
P < 0.001
High-Upvs Low-Down
adjusted HR 6.08 (95% CI 2.56–14.45); P < 0.001
- Patients with events during median WCD wear 68 (IQR 44-90) days
- 58 patients (6%) experienced 69 events
Observational data: associations, not effects.
Further findings
Rise of >5 bpm in weekly average NHR from preceding week
| HR (95% CI) | P value | ||
|---|---|---|---|
| Rise >5 bpmComposite event | 2.51 (1.22–5.18) | P = 0.012 | |
| Rise >5 bpmTotal mortality | 11.21 (3.55–35.37) | P < 0.001 | |
| Rise >5 bpmCV hospitalization | 2.70 (1.51–4.82) | P < 0.001 | |
| 0.050.21520Hazard ratio (log scale) |
Original publication
Dynamic changes in nocturnal heart rate predict short-term cardiovascular events in patients using the wearable cardioverter-defibrillator: from the WEARIT-France cohort study. Europace. Published 6 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →