Heart failure & cardiomyopathies

Early Outcomes in Patients With LVAD Undergoing Heart Transplant via Use of the SherpaPak Cardiac Transport System

Circ Heart FailPublished Retrospective cohort study

Authors' conclusion

SherpaPak use was associated with improved early post-HT outcomes among patients with LVAD undergoing HT.

Study context

Population
Patients with durable LVAD undergoing heart transplant
Participants
149 vs 178
Exposure
SherpaPak vs traditional cold storage
  • SherpaPakn = 149
  • Traditional cold storagen = 178reference
Outcome
Primary graft dysfunction (PGD)
Methodological detailsmulticentre registry, propensity matched analysis
  • Multicentre registry
  • Propensity matched analysis

Main finding

As reported in the abstract

SherpaPak vs Traditional cold storageAdjusted odds ratio (95% CI)P value
PGD
0.56(0.32–0.99)
P = 0.045
Severe PGD
0.31(0.13–0.75)
P = 0.009

Observational data: associations, not effects.

Further findings

ICU length of stay (propensity matched) · trend · propensity matched analysis

P = 0.09

Hospital length of stay (propensity matched) · trend · propensity matched analysis

P = 0.06

30-day and 1-year survival

Similar between groups

Original publication

Early Outcomes in Patients With LVAD Undergoing Heart Transplant via Use of the SherpaPak Cardiac Transport System. Circ Heart Fail. Published 11 April 2024. doi:10.1161/circheartfailure.123.010904

Composed by AI from the published abstract and checked against it. How Briefs are made →

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